Title : Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin.

Pub. Date : 2004 Apr

PMID : 15057963






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The AA gammaH2AX IF was distinguished from the DI-gammaH2AX IF by: 1) its greater intensity; 2) its prevention by caspase inhibitor zVAD-FMK; and 3) the concurrent activation of caspase-3 in the same cells. gammah2ax caspase 3 Homo sapiens