Title : Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase.

Pub. Date : 2004 Apr

PMID : 15056469






3 Functional Relationships(s)
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1 Creatine administration significantly increased brain concentrations of both creatine and PCr in the UbMi-CK knockout mice. Creatine creatine kinase, mitochondrial 1, ubiquitous Mus musculus
2 Creatine administration significantly increased brain concentrations of both creatine and PCr in the UbMi-CK knockout mice. Creatine creatine kinase, mitochondrial 1, ubiquitous Mus musculus
3 Creatine administration to the UbMi-CK-deficient mice exerted significant neuroprotective effects against MPTP toxicity that were comparable in magnitude to those seen in wild-type mice. Creatine creatine kinase, mitochondrial 1, ubiquitous Mus musculus