Title : Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones.

Pub. Date : 2004 Apr 6

PMID : 15051872






1 Functional Relationships(s)
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1 In fetal rat calvarial cells, elevating [Ca2+]o and treatment with gadolinium, a nonpermeant CaR agonist, resulted in phosphorylation of the extracellular signal-regulated kinases 1 and 2, Akt, and glycogensynthase kinase 3beta, consistent with signals of cell survival and proliferation. Gadolinium calcium-sensing receptor Rattus norvegicus