Title : Prostaglandin E2 activates outwardly rectifying Cl(-) channels via a cAMP-dependent pathway and reduces cell motility in rat osteoclasts.

Pub. Date : 2004 Jul

PMID : 15044156






1 Functional Relationships(s)
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1 The PGE(2)-induced Cl(-) current was inhibited by pretreatment with guanosine 5"-O-2-(thiodiphosphate) (GDPbetaS), Rp-adenosine 3",5"-cyclic monophosphorothioate (Rp-cAMPS), N-(2-[p-bromocinnamylamino]ethyl)-5-isoquinolinesulfonamide dihydrochloride (H-89), and protein kinase A inhibitors. guanosine 5'-O-(2-thiodiphosphate) calmodulin 2, pseudogene 1 Rattus norvegicus