Title : Oxidant-mediated impairment of nitric oxide signaling in sickle cell disease--mechanisms and consequences.

Pub. Date : 2004 Feb

PMID : 15040433

1 Functional Relationships(s)
Compound Name
Protein Name
1 A combination of clinical and knockout-transgenic SCD mouse studies show increased rates of xanthine oxidase-dependent superoxide (O2*-) production and reveal the presence of an oxidative and nitrative inflammatory milieu in the sickle cell vasculature, kidney and liver. Superoxides xanthine dehydrogenase Mus musculus