Pub. Date : 2004 Aug
PMID : 15039452
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We previously found that the biguanide metformin, an antidiabetic agent, causes a significant increase of plasma active GLP-1 level in the presence of dipeptidyl peptidase IV (DPPIV) inhibitor in normal rats. | Metformin | dipeptidylpeptidase 4 | Rattus norvegicus |
2 | We previously found that the biguanide metformin, an antidiabetic agent, causes a significant increase of plasma active GLP-1 level in the presence of dipeptidyl peptidase IV (DPPIV) inhibitor in normal rats. | Metformin | dipeptidylpeptidase 4 | Rattus norvegicus |
3 | These results demonstrate that the combination therapy of metformin with DPPIV inhibitor leads to reduced food intake and body weight gain, most likely through the significant increase of plasma GLP-1 level. | Metformin | dipeptidylpeptidase 4 | Rattus norvegicus |