Title : The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling.

Pub. Date : 2004 May 21

PMID : 15031292






1 Functional Relationships(s)
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1 Here, we show that active c-Abl stimulates APP/Fe65-mediated gene transcription and that this effect is mediated by phosphorylation of Fe65 on tyrosine 547 within its second PTB domain. Tyrosine amyloid beta precursor protein binding family B member 1 Homo sapiens