Pub. Date : 2004 Jul
PMID : 15026302
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Renal expression of osmotically responsive cation channel TRPV4 is restricted to water-impermeant nephron segments. | Water | transient receptor potential cation channel subfamily V member 4 | Homo sapiens |
| 2 | Therefore, TRPV4 is expressed in only those nephron segments that are constitutively (i.e., ATL, TAL, and DCT) or conditionally (i.e., collecting duct) water impermeant and where generation of a substantial transcellular osmotic gradient could be expected. | Water | transient receptor potential cation channel subfamily V member 4 | Homo sapiens |
| 3 | TRPV4 expression is absent from nephron segments exhibiting constitutive water permeability and unregulated apical aquaporin expression (i.e., PT and DTL). | Water | transient receptor potential cation channel subfamily V member 4 | Homo sapiens |