Title : Effects of valproate on xenobiotic biotransformation in rat liver. In vivo and in vitro experiments.

Pub. Date : 1992 Jun 19

PMID : 1502013






1 Functional Relationships(s)
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1 In both models the cytochrome P-450 content and the enzymatic activities of 7-ethoxycoumarin O-deethylase, aldrin epoxidase and glutathione S-transferase were determined in valproate-treated hepatocytes, in controls and in phenobarbital-induced cells. Valproic Acid hematopoietic prostaglandin D synthase Rattus norvegicus