Title : Identification of principal cytochrome P-450 in triphenyltin metabolism in rats.

Pub. Date : 2004 Mar 14

PMID : 15019098






8 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Identification of principal cytochrome P-450 in triphenyltin metabolism in rats. triphenyltin cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus
2 The in vivo and in vitro metabolism of triphenyltin using rat hepatic cytochrome P-450 (CYP) systems was investigated to confirm the specific CYP that is closely related to triphenyltin metabolism. triphenyltin cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus
3 The in vivo and in vitro metabolism of triphenyltin using rat hepatic cytochrome P-450 (CYP) systems was investigated to confirm the specific CYP that is closely related to triphenyltin metabolism. triphenyltin cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus
4 The in vivo and in vitro metabolism of triphenyltin using rat hepatic cytochrome P-450 (CYP) systems was investigated to confirm the specific CYP that is closely related to triphenyltin metabolism. triphenyltin cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus
5 The in vivo and in vitro metabolism of triphenyltin using rat hepatic cytochrome P-450 (CYP) systems was investigated to confirm the specific CYP that is closely related to triphenyltin metabolism. triphenyltin cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus
6 The in vivo and in vitro metabolism of triphenyltin using rat hepatic cytochrome P-450 (CYP) systems was investigated to confirm the specific CYP that is closely related to triphenyltin metabolism. triphenyltin cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus
7 No significant sex differences occurred between the in vivo and in vitro metabolic patterns of the chemical, indicating that the principal CYP for triphenyltin metabolism in rats is not a sex-specific form of CYP. triphenyltin cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus
8 Taken together, these findings suggest that CYP2C6 is the principal CYP for the triphenyltin metabolism in rats. triphenyltin cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus