Pub. Date : 2004 Feb 27
PMID : 15013450
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this paper, it was shown that the deletion of the oxysterol binding protein homologue 3 (OSH3) gene confers hyper resistance against ISP-1, an inhibitor of sphingolipid biosynthesis, in the yeast Saccharomyces cerevisiae. | Sphingolipids | oxysterol-binding protein related protein OSH3 | Saccharomyces cerevisiae S288C |
| 2 | Taken together, it is suggested that the expression levels of the OSH3 gene influence the ISP-1 sensitivity of S. cerevisiae, and the sphingolipids are necessary for normal mitotic spindle formation in which the Osh3p may play a pivotal role. | Sphingolipids | oxysterol-binding protein related protein OSH3 | Saccharomyces cerevisiae S288C |