Title : Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX.

Pub. Date : 2004 Feb 23

PMID : 15012984






1 Functional Relationships(s)
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1 The inhibition of the tumor-associated transmembrane carbonic anhydrase IX (CA IX) isozyme possessing an extracellular active site has been investigated with a series of positively-charged, pyridinium derivatives of sulfanilamide, homosulfanilamide and 4-aminoethylbenzenesulfonamide. Sulfanilamide carbonic anhydrase 9 Homo sapiens