Title : Dual effects of adenosine on acetylcholine release from myenteric motoneurons are mediated by junctional facilitatory A(2A) and extrajunctional inhibitory A(1) receptors.

Pub. Date : 2004 Mar

PMID : 14993098






1 Functional Relationships(s)
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1 Although inhibition of ecto-5"-nucleotidase by alpha,beta-methylene ADP (200 microm) or by concanavalin A (0.1 mg ml(-1)) attenuated endogenous adenosine formation from AMP, analysed by HPLC, the corresponding reduction in [(3)H]ACh release only became evident when stimulation of the myenteric plexus was prolonged to over 250 s. 5. Adenosine Monophosphate 5' nucleotidase, ecto Rattus norvegicus