Title : Emodin-induced apoptosis through p53-dependent pathway in human hepatoma cells.

Pub. Date : 2004 Mar 19

PMID : 14987952






1 Functional Relationships(s)
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1 Besides, HepG2/C3A cells were found to be arrested in G(2)/M phase after the cells were treated with 60 microM emodin for 48 h. Moreover, significant increase in the levels of apoptosis-related signals such as p53 (419.3 pg/ml), p21 (437.4 units/ml), Fas (6.6 units/ml), and caspase-3 (35.4 pmol/min) were observed in emodin treated HepG2/C3A cells. ammonium ferrous sulfate tumor protein p53 Homo sapiens