Title : Sphingolipid signalling: molecular basis and role in TNF-alpha-induced cell death.

Pub. Date : 2002 Dec 20

PMID : 14987386






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1 Sphingolipid signalling: molecular basis and role in TNF-alpha-induced cell death. Sphingolipids tumor necrosis factor Homo sapiens
2 This review summarises current knowledge of the signalling functions of sphingolipids, especially in the regulation of tumour necrosis factor [alpha] (TNF-[alpha])-mediated cytotoxic effects. Sphingolipids tumor necrosis factor Homo sapiens
3 On the basis of recent observations, a working model is proposed for the molecular mechanisms underlying regulation of sphingolipid generation following TNF-[alpha] receptor 1 activation. Sphingolipids tumor necrosis factor Homo sapiens