Pub. Date : 2004 Jan
PMID : 14971644
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arsenite induces HIF-1alpha and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells. | arsenite | vascular endothelial growth factor A | Homo sapiens |
| 2 | Arsenite also increases the expression of VEGF through the induction of HIF-1. | arsenite | vascular endothelial growth factor A | Homo sapiens |
| 3 | We also found that arsenite activates PI3K and Akt that are required for arsenite-induced expression of HIF-1alpha and VEGF. | arsenite | vascular endothelial growth factor A | Homo sapiens |
| 4 | We also found that arsenite activates PI3K and Akt that are required for arsenite-induced expression of HIF-1alpha and VEGF. | arsenite | vascular endothelial growth factor A | Homo sapiens |
| 5 | The induction of HIF-1 and VEGF by arsenite can not be inhibited by MAP kinase inhibitors. | arsenite | vascular endothelial growth factor A | Homo sapiens |
| 6 | These data indicate that the arsenite-induced activation of PI3K/Akt signaling and the expression of HIF-1 and VEGF through the generation of ROS could be an important mechanism in the arsenite-induced carcinogenesis. | arsenite | vascular endothelial growth factor A | Homo sapiens |
| 7 | These data indicate that the arsenite-induced activation of PI3K/Akt signaling and the expression of HIF-1 and VEGF through the generation of ROS could be an important mechanism in the arsenite-induced carcinogenesis. | arsenite | vascular endothelial growth factor A | Homo sapiens |