Title : Melatonin reduces oxidative stress in surgical neonates.

Pub. Date : 2004 Feb

PMID : 14966737






2 Functional Relationships(s)
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1 The aim of this study has been to determine if melatonin would lower interleukin (IL)-6, IL-8, tumor necrosis factor alpha (TNF-alpha) and nitrite/nitrate (NOx) levels and modify serum inflammation parameters, improving the clinical course of surgical neonates. Melatonin C-X-C motif chemokine ligand 8 Homo sapiens
2 In group 1a the immediate postoperative values of cytokines were significantly higher than group 1b and group 2, but a significant improvement was observed after administration of melatonin with significantly lower levels of IL-6 and IL-8 with respect to group 2. Melatonin C-X-C motif chemokine ligand 8 Homo sapiens