Title : Effect of FK506 on donor T-cell functions that are responsible for graft-versus-host disease and graft-versus-leukemia effect.

Pub. Date : 2004 Feb 15

PMID : 14966413






1 Functional Relationships(s)
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1 CONCLUSIONS: FK506 inhibits both GvHD and GvL activity when given at clinical doses by inhibiting donor T-cell expansion, donor anti-host T-cell reactivity, and Th1 immune responses. Tacrolimus negative elongation factor complex member C/D Homo sapiens