Pub. Date : 2004 Jul
PMID : 14966081
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Heparin affects signaling pathways stimulated by fibroblast growth factor-1 and -2 in type II cells. | Heparin | fibroblast growth factor 1 | Rattus norvegicus |
| 2 | Heparin, a model for sulfated components of basement membrane matrices, is known to inhibit fibroblast growth factor (FGF)-2-stimulated DNA synthesis as well as gene expression of FGF-2 and its receptor in AT2 cells. | Heparin | fibroblast growth factor 1 | Rattus norvegicus |
| 3 | High-dose heparin reduced FGF-1- or FGF-2-stimulated phosphorylation of mitogen-activated protein kinase kinases (MEK1/2), p44/42 mitogen-activated protein kinases (MAPK/ERK1/2), stress-activated protein kinase/c-Jun NH(2)-terminal kinase, Akt/protein kinase B, and p90(RSK). | Heparin | fibroblast growth factor 1 | Rattus norvegicus |