Title : Increased iNOS activity is essential for intestinal epithelial tight junction dysfunction in endotoxemic mice.

Pub. Date : 2004 Mar

PMID : 14770040






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 iNOS was inhibited using intraperitoneal L-N(6)-(1-iminoethyl)lysine (L-NIL; 5 mg/kg). N(6)-(1-iminoethyl)lysine nitric oxide synthase 2, inducible Mus musculus
2 iNOS was inhibited using intraperitoneal L-N(6)-(1-iminoethyl)lysine (L-NIL; 5 mg/kg). N(6)-(1-iminoethyl)lysine nitric oxide synthase 2, inducible Mus musculus
3 Pharmacologic inhibition of iNOS activity using L-NIL or genetic ablation of the iNOS gene ameliorated LPS-induced changes in TJ protein expression and gut mucosal barrier function. N(6)-(1-iminoethyl)lysine nitric oxide synthase 2, inducible Mus musculus