Title : TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation.

Pub. Date : 2004 Mar

PMID : 14766535






2 Functional Relationships(s)
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1 Inhibition of TNF-alpha-induced NF-kappa B activation by selected NF-kappa B inhibitors, curcumin and triptolide, prevented the increase in Caco-2 TJ permeability, indicating that NF-kappa B activation was required for the TNF-alpha-induced increase in Caco-2 TJ permeability. triptolide tumor necrosis factor Homo sapiens
2 Inhibition of TNF-alpha-induced NF-kappa B activation by selected NF-kappa B inhibitors, curcumin and triptolide, prevented the increase in Caco-2 TJ permeability, indicating that NF-kappa B activation was required for the TNF-alpha-induced increase in Caco-2 TJ permeability. triptolide tumor necrosis factor Homo sapiens