Title : Signaling the brain in systemic inflammation: the role of complement.

Pub. Date : 2004 Jan 1

PMID : 14766418






2 Functional Relationships(s)
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1 For instance, its derivatives C3a, C3b, iC3b, C5a, and C5b-9 independently induce the production by myeloid and non-myeloid cells of the cytokines interleukin (IL)-1(, IL-6 and tumor necrosis factor-(, and of prostaglandin (PG)E2, all putative mediators of fever. Dinoprostone hemolytic complement Mus musculus
2 The purpose of this article is to review the studies that have led us to conclude that C5a, Kc and Kc-generated PGE2 may be integrally involved in the pathogenesis of LPS fever. Dinoprostone hemolytic complement Mus musculus