Title : Adrenal sensitivity to adrenocorticotropin 1-24 is reduced in patients with autoimmune polyglandular syndrome.

Pub. Date : 2004 Feb

PMID : 14764780






3 Functional Relationships(s)
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1 F, A, and DHEA responses to ACTH were dose dependent in both groups. Dehydroepiandrosterone proopiomelanocortin Homo sapiens
2 On the other hand, F, A, and DHEA responses to 250 microg ACTH in AP were not different from those in CS. Dehydroepiandrosterone proopiomelanocortin Homo sapiens
3 In conclusion, patients with autoimmune diseases who displayed a normal basal adrenal function showed a loss of F, A, and DHEA response to the very low ACTH dose, although they were normal responders to the high ACTH dose. Dehydroepiandrosterone proopiomelanocortin Homo sapiens