Title : PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion.

Pub. Date : 2004 Apr 16

PMID : 14761976






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 PIKE-A directly binds to activated Akt but not PI 3-kinase in a guanine nucleotide-dependent way and stimulates the kinase activity of Akt. Guanine Nucleotides ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Homo sapiens