Pub. Date : 2003 Sep
PMID : 14756309
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Antisense-mediated down-regulation of putrescine N-methyltransferase activity in transgenic Nicotiana tabacum L. can lead to elevated levels of anatabine at the expense of nicotine. | anatabine | putrescine N-methyltransferase 1 | Nicotiana tabacum |
| 2 | Several antisense-PMT transformed root lines, and also leaf tissues of regenerated transformed plants, showed a substantial increase in anatabine content relative to controls. | anatabine | putrescine N-methyltransferase 1 | Nicotiana tabacum |
| 3 | We suggest that elevated anatabine levels in antisense-PMT lines are a direct consequence of a relative oversupply of nicotinic acid which, in the absence of adequate levels of 1-methyl-delta(1)-pyrrolinium cation (the ultimate product of PMT activity), is used to synthesise anatabine directly. | anatabine | putrescine N-methyltransferase 1 | Nicotiana tabacum |
| 4 | We suggest that elevated anatabine levels in antisense-PMT lines are a direct consequence of a relative oversupply of nicotinic acid which, in the absence of adequate levels of 1-methyl-delta(1)-pyrrolinium cation (the ultimate product of PMT activity), is used to synthesise anatabine directly. | anatabine | putrescine N-methyltransferase 1 | Nicotiana tabacum |
| 5 | We suggest that elevated anatabine levels in antisense-PMT lines are a direct consequence of a relative oversupply of nicotinic acid which, in the absence of adequate levels of 1-methyl-delta(1)-pyrrolinium cation (the ultimate product of PMT activity), is used to synthesise anatabine directly. | anatabine | putrescine N-methyltransferase 1 | Nicotiana tabacum |
| 6 | As is discussed, no naturally occurring species or varieties of Nicotiana are known that typically produce high levels of anatabine in root or leaf tissues, meaning that the antisense PMT transgenics produced in this study have no natural counterpart. | anatabine | putrescine N-methyltransferase 1 | Nicotiana tabacum |