Title : Hephaestin is a ferroxidase that maintains partial activity in sex-linked anemia mice.

Pub. Date : 2004 May 15

PMID : 14751926






2 Functional Relationships(s)
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1 Hephaestin (Hp) plays an important role in intestinal iron absorption and is predicted to be a ferroxidase based on significant sequence identity to the serum multicopper ferroxidase ceruloplasmin. Iron hephaestin Mus musculus
2 We suggest that hephaestin, by way of its ferroxidase activity, facilitates iron export from intestinal enterocytes, most likely in cooperation with the basolateral iron transporter, Ireg1. Iron hephaestin Mus musculus