Title : Phencyclidine-induced behaviour in mice prevented by methylene blue.

Pub. Date : 2004 Feb

PMID : 14748849






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This effect is blocked by nitric oxide synthase (NOS) inhibitors, suggesting that nitric oxide plays an important role in this effect of phencyclidine. Phencyclidine nitric oxide synthase 1, neuronal Mus musculus
2 The results from the present study further support the suggestion that the nitric oxide synthase/guanylate cyclase pathway is involved in pharmacological and behavioural effects of phencyclidine. Phencyclidine nitric oxide synthase 1, neuronal Mus musculus
3 Since phencyclidine as well exerts psychotomimetic characteristics, agents that interfere with the nitric oxide synthase/guanylate cyclase pathway may be of therapeutic value also in the treatment of schizophrenia. Phencyclidine nitric oxide synthase 1, neuronal Mus musculus