Title : Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil).

Pub. Date : 2004 Feb

PMID : 14744950






1 Functional Relationships(s)
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1 Screening of 10 cDNA-expressed recombinant human UDP-glucuronosyltransferase (UGT) enzymes showed that only UGT1A4 exhibited catalytic activity with respect to the formation of the glucuronide of posaconazole. posaconazole UDP glucuronosyltransferase family 1 member A4 Homo sapiens