Pub. Date : 2004 Feb
PMID : 14744950
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Screening of 10 cDNA-expressed recombinant human UDP-glucuronosyltransferase (UGT) enzymes showed that only UGT1A4 exhibited catalytic activity with respect to the formation of the glucuronide of posaconazole. | Glucuronides | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |
| 2 | The formation of glucuronide by human liver microsomes and UGT1A4 was inhibited by bilirubin, a known inhibitor of UGT1A4. | Glucuronides | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |
| 3 | The formation of glucuronide by human liver microsomes and UGT1A4 was inhibited by bilirubin, a known inhibitor of UGT1A4. | Glucuronides | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |
| 4 | There was a high correlation (r =0.90) between the rate of formation of glucuronide, determined in 10 human liver microsomal samples, and trifluoperazine glucuronidation catalyzed by UGT1A4. | Glucuronides | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |