Title : Different mechanisms mediate uptake of lead in a rat astroglial cell line.

Pub. Date : 2004 Feb

PMID : 14736998






2 Functional Relationships(s)
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1 Cells treated with the iron chelator deferoxamine displayed higher levels of the iron transporter divalent metal transporter 1 (DMT1) mRNA and protein, and consistent with increased DMT1 expression, the treated cells displayed greater uptake of Pb in the buffer at pH 5.5 but not at pH 7.4. Iron RoBo-1 Rattus norvegicus
2 Cells treated with the iron chelator deferoxamine displayed higher levels of the iron transporter divalent metal transporter 1 (DMT1) mRNA and protein, and consistent with increased DMT1 expression, the treated cells displayed greater uptake of Pb in the buffer at pH 5.5 but not at pH 7.4. Iron RoBo-1 Rattus norvegicus