Pub. Date : 2004 Feb
PMID : 14736953
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dexamethasone regulates AP-1 to repress TNF-alpha induced MCP-1 production in human glomerular endothelial cells. | Dexamethasone | C-C motif chemokine ligand 2 | Homo sapiens |
| 2 | CONCLUSIONS: These data demonstrate that while TNF-alpha induced MCP-1 production is mediated by the cooperative action of NF-kappa B and AP-1 in HGEC, dexamethasone represses TNF-alpha induced MCP-1 production via suppression of AP-1 binding activity. | Dexamethasone | C-C motif chemokine ligand 2 | Homo sapiens |