Title : Germ-line mutations in BRCA1 or BRCA2 in the normal breast are associated with altered expression of estrogen-responsive proteins and the predominance of progesterone receptor A.

Pub. Date : 2004 Mar

PMID : 14732925






1 Functional Relationships(s)
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1 This is likely to lead to changes in progesterone signaling in hormone-dependent tissues, which may be a factor in the increased risk of cancer in these tissues in women with germ-line BRCA1 or BRCA2 mutations. Progesterone BRCA1 DNA repair associated Homo sapiens