Title : The role of interleukin-1 and tumor necrosis factor alpha in the neurochemical and neuroendocrine responses to endotoxin.

Pub. Date : 1992 Dec

PMID : 1473014






1 Functional Relationships(s)
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1 Both interleukin-1 (IL-1) and endotoxin (lipopolysaccharide, LPS) are potent activators of the hypothalamo-pituitary-adrenal (HPA) axis, and they also increase cerebral norepinephrine metabolism and tryptophan. Norepinephrine interleukin 1 complex Mus musculus