Title : Glutathione S-transferase overexpression protects against anthracycline-induced H9C2 cell death.

Pub. Date : 2004 Jun

PMID : 14726301






2 Functional Relationships(s)
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1 The DOX-induced increase in ROS was reduced to control levels by maximal GST overexpression. Reactive Oxygen Species hematopoietic prostaglandin D synthase Rattus norvegicus
2 Coincident with this elimination of oxidative stress, there was a reduction in both Trypan blue and TUNEL-positive cells, indicating that GST overexpression reduced both ROS and cell death in this model system. Reactive Oxygen Species hematopoietic prostaglandin D synthase Rattus norvegicus