Pub. Date : 2003 Dec
PMID : 14725353
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: At pH 6.0, H57K-, H57R-, H121K-, and H121R-hPepT1 led to a 97%, 90%, 45%, and 75% decrease in [3H]Gly-Sar uptake into HEK293 cells, respectively. | Glycine | solute carrier family 15 member 1 | Homo sapiens |
| 2 | In oocytes expressing H57R-hPepT1, steady-state currents induced by 5 mM Gly-Sar increased with increasing pH (I(max) = 300 nA at pH 8.5), suggesting the binding of protons to H57R. | Glycine | solute carrier family 15 member 1 | Homo sapiens |
| 3 | CONCLUSIONS: H57R-hPepT1 is able to bind protons at a relatively basic pH, resulting in facilitation of transport of Gly-Sar by hPepT1 at higher pH. | Glycine | solute carrier family 15 member 1 | Homo sapiens |
| 4 | CONCLUSIONS: H57R-hPepT1 is able to bind protons at a relatively basic pH, resulting in facilitation of transport of Gly-Sar by hPepT1 at higher pH. | Glycine | solute carrier family 15 member 1 | Homo sapiens |