Title : Novel neuroprotective K+ channel inhibitor identified by high-throughput screening in yeast.

Pub. Date : 2004 Jan

PMID : 14722253






3 Functional Relationships(s)
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1 Inhibition of Kv2.1 channels decreased in the presence of the external pore blocker tetraethylammonium (TEA) and depended on a residue required for extracellular TEA action, suggesting that the identified compound targets the external mouth of the channel. Tetraethylammonium potassium voltage-gated channel subfamily B member 1 Homo sapiens
2 Inhibition of Kv2.1 channels decreased in the presence of the external pore blocker tetraethylammonium (TEA) and depended on a residue required for extracellular TEA action, suggesting that the identified compound targets the external mouth of the channel. Tetraethylammonium potassium voltage-gated channel subfamily B member 1 Homo sapiens
3 Inhibition of Kv2.1 channels decreased in the presence of the external pore blocker tetraethylammonium (TEA) and depended on a residue required for extracellular TEA action, suggesting that the identified compound targets the external mouth of the channel. Tetraethylammonium potassium voltage-gated channel subfamily B member 1 Homo sapiens