Title : Transport of pharmacologically active proline derivatives by the human proton-coupled amino acid transporter hPAT1.

Pub. Date : 2004 Apr

PMID : 14718599






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This study was performed to investigate whether the recently discovered human proton-coupled amino acid transporter 1 (hPAT1) is capable of transporting such pharmacologically relevant proline derivatives and also GABA analogs. gamma-Aminobutyric Acid solute carrier family 36 member 1 Homo sapiens
2 This study was performed to investigate whether the recently discovered human proton-coupled amino acid transporter 1 (hPAT1) is capable of transporting such pharmacologically relevant proline derivatives and also GABA analogs. gamma-Aminobutyric Acid solute carrier family 36 member 1 Homo sapiens
3 We conclude that 1) the substrate specificity of hPAT1 is very much broader than so far reported and 2) the system accepts therapeutically relevant proline and GABA derivatives. gamma-Aminobutyric Acid solute carrier family 36 member 1 Homo sapiens