Title : Inactivation of platelet-derived growth factor receptor by the tumor suppressor PTEN provides a novel mechanism of action of the phosphatase.

Pub. Date : 2004 Apr 9

PMID : 14718524






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This PIP(3) phosphatase activity of PTEN contributes to its tumor suppressor function by inhibition of Akt kinase, a direct target of PIP(3). pip(3) AKT serine/threonine kinase 1 Homo sapiens