Title : Ruffling-induced chirality: synthesis, metalation, and optical resolution of highly nonplanar, cyclic, benzimidazole-based ligands.

Pub. Date : 2004 Jan 14

PMID : 14709088






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The rate of racemization for amides 54-57 is strongly dependent on the length of the strap. Amides serine/threonine kinase receptor associated protein Homo sapiens
2 X-ray single-crystal structure analysis of the Ni(II) complex of strapped amide 54 reveals that the bis(benzimidazole) core retains its highly ruffled shape, with the two phenyl rings of the macrocycle located anti to the strap. Amides serine/threonine kinase receptor associated protein Homo sapiens