Title : Role of the histidine triad-like motif in nucleotide hydrolysis by the rotavirus RNA-packaging protein NSP2.

Pub. Date : 2004 Mar 12

PMID : 14699117






1 Functional Relationships(s)
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1 Consistent with the structural predictions, we show here using site-specific mutagenesis and ATP docking simulations that the active site for NTP hydrolysis is localized to residues within a 25-A-deep cleft between the C- and N-terminal domains of the NSP2 monomer. Adenosine Triphosphate reticulon 2 Homo sapiens