Title : Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae.

Pub. Date : 2004 Jan 5

PMID : 14697759






1 Functional Relationships(s)
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1 Here we report that in the absence of the AP endonucleases, deletion of two Escherichia coli endonuclease III homologs, NTG1 and NTG2, partially suppresses MMS-induced killing, which indicates that the AP lyase products are deleterious unless they are further processed by an AP endonuclease. Methyl Methanesulfonate endonuclease III Escherichia coli