Title : [Effects of oral cadmium exposure on expression of metallothionein-I and metallothionein-II mRNA in rat prostate].

Pub. Date : 2002 Oct

PMID : 14694715






8 Functional Relationships(s)
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1 [Effects of oral cadmium exposure on expression of metallothionein-I and metallothionein-II mRNA in rat prostate]. Cadmium metallothionein 1 Rattus norvegicus
2 OBJECTIVE: To investigate the possible effects of oral cadmium(Cd) exposure on the expression levels of metallothionein-I and metallothionein-II (MT-I and MT-II) mRNA and the distribution of zinc (Zn) and Cd in rat prostate. Cadmium metallothionein 1 Rattus norvegicus
3 OBJECTIVE: To investigate the possible effects of oral cadmium(Cd) exposure on the expression levels of metallothionein-I and metallothionein-II (MT-I and MT-II) mRNA and the distribution of zinc (Zn) and Cd in rat prostate. Cadmium metallothionein 1 Rattus norvegicus
4 OBJECTIVE: To investigate the possible effects of oral cadmium(Cd) exposure on the expression levels of metallothionein-I and metallothionein-II (MT-I and MT-II) mRNA and the distribution of zinc (Zn) and Cd in rat prostate. Cadmium metallothionein 1 Rattus norvegicus
5 OBJECTIVE: To investigate the possible effects of oral cadmium(Cd) exposure on the expression levels of metallothionein-I and metallothionein-II (MT-I and MT-II) mRNA and the distribution of zinc (Zn) and Cd in rat prostate. Cadmium metallothionein 1 Rattus norvegicus
6 It was also noted that Cd administration resulted in a significant down-regulation of the expression of MT-I and MT-II mRNA in rat ventral prostate. Cadmium metallothionein 1 Rattus norvegicus
7 In 200 mg/kg Cd group after one and six months, the relative expression levels of MT-I (0.410, 0.339 respectively) and MT-II (0.100, 0.112 respectively) were significantly lower than those of MT-I (0.760, 0.830 respectively) and MT-II (0.429, 0.439 respectively) in control group. Cadmium metallothionein 1 Rattus norvegicus
8 In 200 mg/kg Cd group after one and six months, the relative expression levels of MT-I (0.410, 0.339 respectively) and MT-II (0.100, 0.112 respectively) were significantly lower than those of MT-I (0.760, 0.830 respectively) and MT-II (0.429, 0.439 respectively) in control group. Cadmium metallothionein 1 Rattus norvegicus