Title : AMG531 stimulates megakaryopoiesis in vitro by binding to Mpl.

Pub. Date : 2004 Jan 21

PMID : 14693160






2 Functional Relationships(s)
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1 Treatment of BaF3-Mpl cells with AMG531 or with TPO resulted in rapid tyrosine phosphorylation of Mpl, JAK2, and STAT5. Tyrosine myeloproliferative leukemia virus oncogene Mus musculus
2 Treatment of BaF3-Mpl cells with AMG531 or with TPO resulted in rapid tyrosine phosphorylation of Mpl, JAK2, and STAT5. Tyrosine myeloproliferative leukemia virus oncogene Mus musculus