Title : [Effect of thalidomide on tumor growth in mouse hepatoma H22 model].

Pub. Date : 2003 Dec

PMID : 14693056






3 Functional Relationships(s)
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1 The aim of this research was to observe the effect of thalidomide on tumor homograft growth in mouse H22 model and to investigate the mechanisms involved and its curative possibility to hepatoma. Thalidomide histocompatibility 22 Mus musculus
2 CONCLUSION: Thalidomide can significantly induce apoptosis and inhibit angiogenesis in mouse H22 model when it is used at the beginning of carcinogenesis, but it has no obvious anti-angiogenic efficacy on the grown tumor. Thalidomide histocompatibility 22 Mus musculus
3 Thalidomide cannot inhibit VEGF mRNA expression of grafted H22 tumor in mouse. Thalidomide histocompatibility 22 Mus musculus