Title : Clofibrate, a peroxisome-proliferator, enhances reverse cholesterol transport through cytochrome P450 activation and oxysterol generation.

Pub. Date : 2003 Dec

PMID : 14690017






1 Functional Relationships(s)
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1 Clofibrate increases cytochrome P450 content and the resulting oxysterol generation may partly mediate the clofibrate-induced up-regulattion of LXRa and ABCA1, which are related to reverse cholesterol transport. Cholesterol ATP binding cassette subfamily A member 1 Rattus norvegicus