Title : Role of direct RhoA-phospholipase D1 interaction in mediating adenosine-induced protection from cardiac ischemia.

Pub. Date : 2004 Feb

PMID : 14688204






1 Functional Relationships(s)
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1 In an established cardiac myocyte model of preconditioning using the cultured chick embryo heart cells, overexpression of the RhoA-noninteracting PLD1 mutant I870R selectively blocked the A3 agonist (Cl-IBMECA, 10 nM)-induced cardioprotection. 2-chloro-N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamide ras homolog family member A Gallus gallus