Title : Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase.

Pub. Date : 2004 Jan 5

PMID : 14684333






1 Functional Relationships(s)
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Protein Name
Organism
1 In addition, a very short bond of 1.78A between the zinc ion and the coordinated nitrogen atom of the sulfamate moiety is observed, which may explain the high affinity of this inhibitor for hCA II (K(i) of 10nM). Nitrogen carbonic anhydrase 2 Homo sapiens