Title : Effects of dose-reduced Medac L-asparaginase on coagulation in trial ALL-BFM 2000.

Pub. Date : 2003 Nov-Dec

PMID : 14677096






1 Functional Relationships(s)
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1 RESULTS AND CONCLUSIONS: This analysis is the first to show that 5000 IU/m (2) of the Medac L-ASP leads to a less pronounced decrease of the plasma AT III and fibrinogen concentrations during induction therapy (after the 5 (th) L-ASP dose), as compared to previous BFM protocols which used the Medac L-ASP in a dosage of 10 000 IU/m (2). bfm asparaginase and isoaspartyl peptidase 1 Homo sapiens