Pub. Date : 2004 Jan 15
PMID : 14676270
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In neutrophils and other phagocytic cells, the small GTPase Rac is an essential regulator of a multi-component NADPH oxidase that produces high levels of superoxide, which kills invading pathogens. | Superoxides | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | In many other cell types, Rac and newly discovered relatives of the neutrophil burst oxidase and its subunits have been found associated with production of reactive oxygen species, implicating superoxide production in a wide range of cellular processes not related to host defense. | Superoxides | AKT serine/threonine kinase 1 | Homo sapiens |