Pub. Date : 2003 Dec
PMID : 14670979
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PGE2, a major arachidonic acid metabolite produced in the kidney, acts on 4 receptor subtypes, EP1 through EP4, but the pathophysiological importance of the PGE2/EP subtypes in the development of hypertensive renal injury remains to be elucidated. | Dinoprostone | prostaglandin E receptor 1 | Rattus norvegicus |
| 2 | These findings indicate that the PGE2/EP1 signaling pathway plays a crucial role in the development of renal injury in SHRSP. | Dinoprostone | prostaglandin E receptor 1 | Rattus norvegicus |